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Article

Clinical and Genetic Features of a Large Monocentric Series of Familial Non-Medullary Thyroid Cancers.

Frontiers in endocrinology - 1 Jan 2020

Cirello Valentina, Colombo Carla, Karapanou Olga, Pogliaghi Gabriele, Persani Luca, Fugazzola Laura

Abstract excerpt

Several low penetration susceptibility risk loci or genes have been proposed in recent years with a possible causative role for familial non-medullary thyroid cancer (FNMTC), though the results are still not conclusive or reliable. Among all the candidates, here fully reviewed, a new extremely rare germline variant c.3607A>G (p.Y1203H) of the DUOX2 gene, has been recently reported to co-segregate with the...

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Identifiers

PMID: 33488516
DOI: 10.3389/fendo.2020.589340
PMCID: PMC7817808

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