Article
Genetic heterogeneity in familial nonmedullary thyroid carcinoma: exclusion of linkage to RET, MNG1, and TCO in 56 families. NMTC Consortium.
The Journal of clinical endocrinology and metabolism - 1 Jun 1999
Lesueur F, Stark M, Tocco T, Ayadi H, Delisle M J, Goldgar D E, Schlumberger M, Romeo G, Canzian F
Abstract excerpt
Epidemiological studies show a very high relative risk for first degree relatives of probands with thyroid cancer. The familial form of nonmedullary thyroid carcinoma (NMTC) gives a more severe phenotype and appears earlier than its sporadic counterpart. Moreover, benign thyroid pathologies are often observed in NMTC kindreds. Little is known about the genetic risk factors of the disease. To study them, an...
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