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Article

A comprehensive analysis of MNG1, TCO1, fPTC, PTEN, TSHR, and TRKA in familial nonmedullary thyroid cancer: confirmation of linkage to TCO1.

The Journal of clinical endocrinology and metabolism - 1 Aug 2001

Bevan S, Pal T, Greenberg C R, Green H, Wixey J, Bignell G, Narod S A, Foulkes W D, Stratton M R, Houlston R S

Abstract excerpt

About 5% of nonmedullary thyroid cancer is familial. These familial nonmedullary thyroid cancer cases are characterized by an earlier age of onset, more aggressive phenotype, and in some families a high propensity to benign thyroid disease. Little is known about the genes conferring predisposition to nonmedullary thyroid cancer. Three loci have been identified through genetic linkage: MNG1 on 14q32, TCO1 on...

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Source

Identifiers

PMID: 11502798
DOI: 10.1210/jcem.86.8.7725

Genes

PTEN
TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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