Article
A gene predisposing to familial thyroid tumors with cell oxyphilia maps to chromosome 19p13.2.
American journal of human genetics - 1 Dec 1998
Canzian F, Amati P, Harach H R, Kraimps J L, Lesueur F, Barbier J, Levillain P, Romeo G, Bonneau D
Abstract excerpt
Familial nonmedullary thyroid cancer (FNMTC) is a clinical entity characterized by a phenotype more aggressive than that of its sporadic counterpart. Families with recurrence of nonmedullary thyroid cancer (NMTC) have been repeatedly reported in the literature, and epidemiological data show a ver...
Topics
- Adenoma, Oxyphilic
- Adolescent
- Adult
- Carcinoma, Papillary
- Child
- Chromosome Mapping
- Chromosomes, Human, Pair 19
- Female
- Genes, Dominant
- Genetic Linkage
- Genetic Predisposition to Disease
- Genotype
- Goiter, Nodular
- Humans
- Lod Score
- Male
- Microsatellite Repeats
- Middle Aged
