Article
Estimating the degree of identity by descent in consanguineous couples.
Human mutation - 1 Dec 2011
Carr Ian M, Markham Sir Alexander F, Pena Sérgio D J
Abstract excerpt
In some clinical and research settings, it is often necessary to identify the true level of "identity by descent" (IBD) between two individuals. However, as the individuals become more distantly related, it is increasingly difficult to accurately calculate this value. Consequently, we have developed a computer program that uses genome-wide SNP genotype data from related individuals to estimate the size and extent...
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