Article
Contribution of the -455G/A polymorphism at the beta-fibrinogen gene to erythrocyte aggregation in patients with coronary artery disease.
Thrombosis and haemostasis - 1 Nov 1999
Weng X, Cloutier G, Genest J
Abstract excerpt
BACKGROUND: A high level of red blood cell (RBC) aggregation has been consistently found in patients with coronary artery disease (CAD) in case-control studies. Plasma fibrinogen has been shown to promote RBC aggregability. The purpose of this study was to investigate the influence of the genetic variability of the beta-fibrinogen gene on RBC aggregation in patients with CAD. METHODS AND RESULTS: The genotype of...
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