Article
Beta-fibrinogen gene G/A-455 polymorphism in relation to fibrinogen concentrations and ischaemic heart disease in Chinese patients with type II diabetes.
Diabetologia - 1 Oct 1999
Lam K S, Ma O C, Wat N M, Chan L C, Janus E D
Abstract excerpt
AIMS/HYPOTHESIS: We investigated the relation between the G/A-455 (Hae III) beta-fibrinogen gene polymorphism and plasma fibrinogen concentration and its role in ischaemic heart disease in 264 Chinese patients with Type II (non-insulin-dependent) diabetes mellitus and 182 non-diabetic control subjects. METHODS: The G/A-455 polymorphism was determined in genomic DNA using polymerase chain reaction and Hae III...
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