Article
Vitamin D binding protein alleles and susceptibility for type 1 diabetes in Germans.
Autoimmunity - 1 Jan 1999
Pani M A, Donner H, Herwig J, Usadel K H, Badenhoop K
Abstract excerpt
Vitamin D has been shown to modulate the immune system thereby preventing the development of diabetes in NOD mice. Since the vitamin D binding protein (DBP) is the main transporter for vitamin D and DBP has immunomodulatory properties itself, we investigated three polymorphic sites within the DBP gene as candidates for type 1 diabetes susceptibility for the first time. 152 Caucasian families with at least one...
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