Article
Common variants of the vitamin D binding protein gene and adverse health outcomes.
Critical reviews in clinical laboratory sciences - 1 Jan 2000
Malik Suneil, Fu Lei, Juras David James, Karmali Mohamed, Wong Betty Y L, Gozdzik Agnes, Cole David E C
Abstract excerpt
The vitamin D binding protein (DBP) is the major plasma carrier for vitamin D and its metabolites, but it is also an actin scavenger, and is the precursor to the immunomodulatory protein, Gc-MAF. Two missense variants of the DBP gene - rs7041 encoding Asp432Glu and rs4588 encoding Thr436Lys - change the amino acid sequence and alter the protein function. They are common enough to generate population-wide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.