Article
Protection from type 1 diabetes by vitamin D receptor haplotypes.
Annals of the New York Academy of Sciences - 1 Oct 2006
Ramos-Lopez Elizabeth, Jansen Thomas, Ivaskevicius Vytautas, Kahles Heinrich, Klepzig Christian, Oldenburg Johannes, Badenhoop Klaus
Abstract excerpt
Vitamin D has been involved in the modulation of calcium and bone metabolism as well as in the immune system, where it suppresses the proliferation of activated T cells. These effects are exerted via the vitamin D receptor (VDR). Polymorphisms within this gene have been exhaustively studied in diverse autoimmune diseases but with inconsistent results. We previously reported a positive association of polymorphisms...
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