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Article

Variability at the uridine diphosphate glucuronosyltransferase 1A1 promoter in human populations and primates.

Pharmacogenetics - 1 Oct 1999

Hall D, Ybazeta G, Destro-Bisol G, Petzl-Erler M L, Di Rienzo A

Abstract excerpt

Variation at the UDP-glucuronosyltransferase (UGT) 1A1 gene promoter is present in humans. Variable numbers of TA repeats in the TATA box of this gene are found which are inversely related to levels of gene expression. We investigated this polymorphism in 658 individuals from a worldwide sample of 15 aboriginal and two admixed human populations. This study shows that there is a great deal of variability across...

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PMID: 10591539

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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