Article
UDP-Glucuronosyltransferase 1A1 gene polymorphisms and total bilirubin levels in an ethnically diverse cohort of women.
Drug metabolism and disposition: the biological fate of chemicals - 1 Aug 2007
Hong Andrew L, Huo Dezheng, Kim Hee-Jin, Niu Qun, Fackenthal Donna L, Cummings Shelly A, John Esther M, West Dee W, Whittemore Alice S, Das Soma, Olopade Olufunmilayo I
Abstract excerpt
The objective of this study was to investigate variations in UGT1A1 polymorphisms and haplotypes among African-American and Caucasian women and to assess whether variants other than UGT1A1*28 are associated with total serum bilirubin levels. The (TA)(n) repeats and 14 single nucleotide polymorphisms (SNPs) in the UGT1A1 gene were genotyped in 335 African Americans and 181 Caucasians. Total serum bilirubin levels...
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