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Article

Identification and classification of p53-regulated genes

7 Dec 1999

Abstract excerpt

Sequence-specific transactivation by p53 is essential to its role as a tumor suppressor. A modified tetracycline-inducible system was established to search for transcripts that were activated soon after p53 induction. Among 9,954 unique transcripts identified by serial analysis of gene expression, 34 were increased more than 10-fold; 31 of these had not previously been known to be regulated by p53. The...

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Identifiers

PMID: 10588737
DOI: 10.1073/pnas.96.25.14517

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Source receipt: pubmed, retrieved 7 Sept 2026.

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