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Article

Higher prevalence of GPIIIa PlA2 polymorphism in siblings of patients with premature coronary heart disease.

Archives of pathology & laboratory medicine - 1 Dec 1999

Goldschmidt-Clermont P J, Coleman L D, Pham Y M, Cooke G E, Shear W S, Weiss E J, Kral B G, Moy T F, Yook R M, Blumenthal R S, Becker D M, Becker L C, Bray P F

Abstract excerpt

BACKGROUND: The Pl(A2) polymorphism of GPIIIa has been associated with unstable coronary syndromes in some studies, but the association has remained debated. None of the previous studies have focused on families at high risk. Risk factors tend to cluster within kindreds with high prevalence of premature coronary heart disease (CHD). Therefore, a heightened prevalence of the Pl(A2) polymorphism among siblings of...

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Identifiers

PMID: 10583927
DOI: 10.5858/1999-123-1223-HPOGPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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