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Article

The pfmdr1 gene is associated with a multidrug-resistant phenotype in Plasmodium falciparum from the western border of Thailand.

Antimicrobial agents and chemotherapy - 1 Dec 1999

Price R N, Cassar C, Brockman A, Duraisingh M, van Vugt M, White N J, Nosten F, Krishna S

Abstract excerpt

On the western border of Thailand, Plasmodium falciparum has become resistant to almost all antimalarial agents. The molecular basis of resistance in these parasite populations has not been well characterized. This study assessed genetic polymorphisms in the pfmdr1 gene in 54 parasites collected from the western border of Thailand to determine the relationship of pfmdr1 copy number and codon mutations with...

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Source

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Identifiers

PMID: 10582887
DOI: 10.1128/AAC.43.12.2943
PMCID: PMC89592

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Source receipt: pubmed, retrieved 7 Sept 2026.

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