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Article

Resistance to antimalarials in Southeast Asia and genetic polymorphisms in pfmdr1.

Antimicrobial agents and chemotherapy - 1 Aug 2003

Pickard Amy L, Wongsrichanalai Chansuda, Purfield Anne, Kamwendo Deborah, Emery Kathryn, Zalewski Christy, Kawamoto Fumihiko, Miller R Scott, Meshnick Steven R

Abstract excerpt

Resistance to antimalarial drugs is a public health problem worldwide. Molecular markers for drug-resistant malaria, such as pfcrt and pfmdr1 polymorphisms, could serve as useful surveillance tools. To evaluate this possibility, sequence polymorphisms in pfcrt (position 76) and pfmdr1 (positions 86, 184, 1034, 1042, and 1246) and in vitro drug sensitivities were measured for 65 Plasmodium falciparum isolates from...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12878499
DOI: 10.1128/AAC.47.8.2418-2423.2003
PMCID: PMC166057

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Source receipt: pubmed, retrieved 7 Sept 2026.

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