Article
Conservation of the cag pathogenicity island of Helicobacter pylori: associations with vacuolating cytotoxin allele and IS605 diversity.
Gastroenterology - 1 Dec 1999
Slater E, Owen R J, Williams M, Pounder R E
Abstract excerpt
BACKGROUND & AIMS: Specific regions of the cag pathogenicity island (PAI) believed to enhance the virulence of Helicobacter pylori, as well as vacuolating cytotoxin gene alleles and IS605 inserts, were investigated to define diversity within infecting strain populations from patients with peptic ulcer disease and from healthy individuals. METHODS: The H. pylori studied comprised 67 isolates from 26 subjects and...
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