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Article

Associations of IGF2 ApaI RFLP and INS VNTR class I allele size with obesity.

European journal of human genetics : EJHG - 1 Jan 2000

O'Dell S D, Bujac S R, Miller G J, Day I N

Abstract excerpt

Body mass index (BMI) is an established epidemiological predictor of coronary disease, diabetes and hypertension. In a previous study of 2560 healthy British Caucasoid males aged 50-61 years (Northwick Park Heart Study II; NPHSII), we showed that IGF2 ApaI AA homozygotes display a mean body weight 3.3 kg lower than GG homozygotes (P = 0.0002) independent of height. Two RFLPs in the insulin (INS) gene, +1127/PstI...

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Share to Body Mass Index
Share to Cohort Studies
Share to Deoxyribonucleases, Type II Site-Specific

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulin

Share to Insulin-Like Growth Factor II

Share to Minisatellite Repeats

Share to Obesity

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 10573016
DOI: 10.1038/sj.ejhg.5200381

Genes

INS
IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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