Article
IGF2 genotype and obesity in men and women across the adult age span.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Apr 2002
Roth S M, Schrager M A, Metter E J, Riechman S E, Fleg J L, Hurley B F, Ferrell R E
Abstract excerpt
We studied a previously reported association between the IGF2 gene's ApaI polymorphism and obesity in 500 healthy men and women (19-90 y). We hypothesized that individuals homozygous for the IGF2 A allele (A/A) would exhibit lower body mass, BMI and DEXA-measured fat mass compared to G/G homozygotes. Subjects were categorized as exhibiting the G/G (n = 241), G/A (n = 197) or A/A (n = 62) genotype. Contrary to our...
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