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Article

Activation of channel activity of the NMDA receptor-PSD-95 complex by guanylate kinase-associated protein (GKAP).

FEBS letters - 24 Sept 1999

Yamada Y, Chochi Y, Ko J A, Sobue K, Inui M

Abstract excerpt

The channel-associated protein PSD-95 functionally modulates NMDA receptor channels, interacting with the channels via PDZ domain of PSD-95. PSD-95 also interacts with guanylate kinase-associated protein (GKAP) through the guanylate kinase-like domain of PSD-95. Here we report that GKAP markedly potentiates the channel activity of the receptor-PSD-95 complex. However, GKAP had no effect on basic properties of the...

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Source

Identifiers

PMID: 10570927
DOI: 10.1016/s0014-5793(99)01171-0

Genes

PSD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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