Article
Shared Early Autoantibody Recognition Events in the Development of Anti‐Sm B/B' in Human Lupus
1 Nov 1999
Abstract excerpt
Many aspects of the immune maturation are uncharted. For ordinary human autoimmune systems there are no complete descriptions of the progression from an initial antigenic epitope to a maximally complex immune response. In this study we have exploited a large serial collection of human sera to investigate the development of the anti-Sm autoimmune response in systemic lupus erythematosus (SLE). The results suggest...
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