Article
Rhodamine123 reveals heterogeneity within murine Lin-, Sca-1+ hemopoietic stem cells.
The Journal of experimental medicine - 1 Jun 1992
Li C L, Johnson G R
Abstract excerpt
Murine bone marrow Lin-, Ly6A/E+ cells have been fractionated on the basis of rhodamine123 retention into Rh123med/hi and Rh123lo subpopulations. These populations have different responses to hemopoietic growth factors with respect to in vitro colony formation. Cells from either fraction were not...
Topics
- Animals
- Antigens, Ly
- Bone Marrow Cells
- Cell Separation
- Colony-Forming Units Assay
- Flow Cytometry
- Fluorescent Dyes
- Granulocyte Colony-Stimulating Factor
- Granulocyte-Macrophage Colony-Stimulating Factor
- Growth Inhibitors
- Hematopoietic Cell Growth Factors
- Hematopoietic Stem Cells
- Interleukin-1
- Interleukin-3
- Interleukin-6
- Leukemia Inhibitory Factor
- Lymphokines
- Macrophage Colony-Stimulating Factor