Article
Characterization of primary isolate-like variants of simian-human immunodeficiency virus.
Journal of virology - 1 Dec 1999
Crawford J M, Earl P L, Moss B, Reimann K A, Wyand M S, Manson K H, Bilska M, Zhou J T, Pauza C D, Parren P W, Burton D R, Sodroski J G, Letvin N L, Montefiori D C
Abstract excerpt
Several different strains of simian-human immunodeficiency virus (SHIV) that contain the envelope glycoproteins of either T-cell-line-adapted (TCLA) strains or primary isolates of human immunodeficiency virus type 1 (HIV-1) are now available. One of the advantages of these chimeric viruses is their application to studies of HIV-1-specific neutralizing antibodies in preclinical AIDS vaccine studies in nonhuman...
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