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Article

Genetic control of hepatic apoB-100 secretion in human apoB transgenic mouse strains.

Journal of lipid research - 1 Nov 1999

Voyiaziakis E, Ko C, O'Rourke S M, Huang L S

Abstract excerpt

Plasma apolipoprotein B (apoB) levels vary widely in the general population and elevated plasma levels of apoB are associated with higher risk for atherosclerotic coronary heart disease. Determination of genetic factors regulating population variance of plasma apoB levels is complicated by the genetic heterogeneity of human populations. Using a congenic human apoB transgenic mouse strain in the C57BL/6 background...

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PMID: 10553004

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