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Article

Modulation of the clastogenic activity of gamma-irradiation in buthionine sulphoximine-mediated glutathione depleted mammalian cells.

International journal of radiation biology - 1 Oct 1999

Chattopadhyay A, Deb S, Chatterjee A

Abstract excerpt

PURPOSE: Chromosome aberrations (CA) were used as an end-point to investigate the effect of buthionine sulphoximine (BSO), a potent glutathione-depleting agent, on the radiosensitivity of mammalian cells. The aim was to obtain information about the role of glutathione (GSH) in physicochemical and biochemical processes in irradiated cells. MATERIALS AND METHODS: CA were scored from first cycle metaphases in...

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Identifiers

PMID: 10549605
DOI: 10.1080/095530099139449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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