Article
Sulforaphane mitigates genotoxicity induced by radiation and anticancer drugs in human lymphocytes.
Mutation research. Genetic toxicology and environmental mutagenesis - 12 Dec 2013
Katoch Omika, Kumar Arun, Adhikari Jawahar S, Dwarakanath Bilikere S, Agrawala Paban K
Abstract excerpt
Sulforaphane, present in cruciferous vegetables such as broccoli, is a dietary anticancer agent. Sulforaphane, added 2 or 20 h following phytohemaglutinin stimulation to cultured peripheral blood lymphocytes of individuals accidentally exposed to mixed γ and β-radiation, reduced the micronucleus frequency by up to 70%. Studies with whole blood cultures obtained from healthy volunteers confirmed the ability of...
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