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Article

Buthionine sulfoximine mediated enhancement of gamma-radiation induced mutation frequency in Drosophila melanogaster.

Mutation research - 1 Apr 1993

Abraham S K, Singh S P, Kesavan P C

Abstract excerpt

Experiments were carried out to investigate whether or not depletion of the glutathione (GSH) level in Drosophila melanogaster larvae with buthionine sulfoximine (BSO) treatment can result in the modulation of the frequency of sex-linked recessive lethal (SLRL) mutations induced by gamma-radiation. Third instar larvae were fed on BSO for 24 h before exposure to 10 Gy gamma-radiation. Immediately after this the...

Topics

Animals
Buthionine Sulfoximine
Drosophila melanogaster
Gamma Rays
Genes, Lethal
Genetic Linkage
Glutathione
Larva
Male
Methionine Sulfoximine
Mutagens
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Radiation-Sensitizing Agents

Source

Identifiers

PMID: 7680760
DOI: 10.1016/0165-7992(93)90066-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7680760-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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