Article

A seleno-hormetine protects bone marrow hematopoietic cells against ionizing radiation-induced toxicity

2018-10-01

Abstract excerpt

2,2’-diselenyldibenzoic acid (DSBA) is a mild thiol peroxidase agent presently in preclinical development. This study reports that the drug has novel seleno-hormetic properties in both murine bone marrow and human liver cells. According with previous in vitro findings, mechanistic aspects of such properties were confirmed to include the activation of Nrf2 transcription factor and an increased expression of downstr...

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Literature Corpus work: 4091d901-60e4-54dc-8927-699ac02950a2
DOI: 10.1101/432286

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