Article
Analysis of HIV cross-resistance to protease inhibitors using a rapid single-cycle recombinant virus assay for patients failing on combination therapies.
AIDS (London, England) - 22 Oct 1999
Race E, Dam E, Obry V, Paulous S, Clavel F
Abstract excerpt
OBJECTIVE: To assess the patterns of HIV phenotypic cross-resistance to protease inhibitors (PI) in patients experiencing viral load rebound on combination therapy including a PI. METHODS: Phenotypic analysis of sensitivity to indinavir, nelfinavir, saquinavir, ritonavir and amprenavir was carried out using a single-cycle recombinant virus assay. Viral protease was sequenced by automated dideoxynucleotide chain...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
