Article
Longitudinal use of phenotypic resistance testing to HIV-1 protease inhibitors in patients developing HAART failure.
Journal of medical virology - 1 Jul 2002
Servais Jean, Plesséria Jean-Marc, Lambert Christine, Fontaine Elodie, Robert Isabelle, Arendt Vic, Staub Thérèse, Schneider François, Hemmer Robert, Schmit Jean-Claude
Abstract excerpt
An "in-house" recombinant virus protease inhibitor susceptibility assay was carried out (median of 3 per patient) retrospectively in 26 patients failing HIV protease inhibitor based therapy at regular intervals to the initiation of the first protease inhibitor. Patients were treated with either indinavir (N = 6), ritonavir (N = 10), or saquinavir (N = 10) and two nucleoside analogues. Second line therapy was...
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