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Article

Intramolecular backfolding of the carboxyl-terminal end of MxA protein is a prerequisite for its oligomerization.

The Journal of biological chemistry - 5 Nov 1999

Di Paolo C, Hefti H P, Meli M, Landis H, Pavlovic J

Abstract excerpt

Mx proteins are large GTPases, which play a pivotal role in the interferon type I-mediated response against viral infections. The human MxA inhibits the replication of several RNA viruses and is organized in oligomeric structures. Using two different experimental approaches, the mammalian two-hybrid system and an interaction dependent nuclear translocation approach, three domains in the carboxyl-terminal moiety...

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PMID: 10542240
DOI: 10.1074/jbc.274.45.32071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Intramolecular backfolding of the carboxyl-terminal end of MxA protein is a prerequisite for its oligomerization.PMID 10542240Read ↗

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