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Article

Identification of N-acetyltransferase 2 genotypes by continuous monitoring of fluorogenic hybridization probes.

Analytical biochemistry - 1 Nov 1999

Blömeke B, Sieben S, Spötter D, Landt O, Merk H F

Abstract excerpt

Three polymorphic sites in the N-acetyltransferase 2 (NAT2) gene were detected using rapid cycle DNA amplification with allele-specific fluorescent probes and melting curve analysis. Two fluorogenic adjacent hybridization probes were designed to NAT2*5A (C(481)T), NAT2*6A (G(590)A), and NAT2*7A (G(857)A). During amplification, probe hybridization is observed as fluorescence resonance energy transfer. The...

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Share to Arylamine N-Acetyltransferase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 10542113
DOI: 10.1006/abio.1999.4288

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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