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Article

Simultaneous determination of 7 N-acetyltransferase-2 single-nucleotide variations by allele-specific primer extension assay.

Clinical chemistry - 1 Jun 2006

Zhu Yusheng, Hein David W, Doll Mark A, Reynolds Kristen K, Abudu Ntei, Valdes Roland, Linder Mark W

Abstract excerpt

BACKGROUND: Genotyping of N-acetyltransferase-2 (NAT2) is useful in predicting the risk for toxicity of NAT2 substrates. Current methods cannot detect the 7 most important single-nucleotide variations in NAT2 simultaneously in 1 tube. METHODS: We developed an assay that uses allele-specific primer extension (ASPE) and microsphere hybridization for the simultaneous detection of 7 single-nucleotide variations in...

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Source

Identifiers

PMID: 16556682
DOI: 10.1373/clinchem.2005.063198

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Simultaneous determination of 7 N-acetyltransferase-2 single-nucleotide variations by allele-specific primer extension assay.PMID 16556682Read ↗

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