Article
Determination of single nucleotide polymorphisms in N-acetyltransferase2 gene using an electrochemical DNA chip and an automated DNA detection system.
Rinsho byori. The Japanese journal of clinical pathology - 1 Mar 2007
Nakamura Naoko, Ito Keiko, Hongo Sadato, Hashimoto Kouji, Furutsuka Miyuki, Kubota Ryuuji, Fukuda Tsuyoshi, Ohno Masako, Azuma Junichi, Gemma Nobuhiro
Abstract excerpt
An electrochemical DNA chip using an electrochemically active intercalator and DNA probe immobilized on a gold electrode has been developed for genetic analysis. In this study, N-acetyltransferase2 (NAT2) gene polymorphisms (C481T G590A G857A) were determined by the electrochemical DNA chip and the automated DNA detection system that performs hybridization reaction, washing, detection, and data analysis. Human...
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