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Article

Ataxia telangiectasia mutated deficiency affects astrocyte growth but not radiosensitivity.

Cancer research - 15 Oct 1999

Gosink E C, Chong M J, McKinnon P J

Abstract excerpt

The cancer-prone neurodegenerative disorder, ataxia telangiectasia (A-T), results from mutations of ATM (ataxia telangiectasia mutated). Individuals with A-T are also hypersensitive to ionizing radiation (IR). Cultured cells from A-T individuals or Atm-/- mice have cell cycle and growth defects and are generally considered radiosensitive. However, it has been shown recently that cell populations in the Atm-/-...

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Source

Identifiers

PMID: 10537312

Genes

ATM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ataxia telangiectasia mutated deficiency affects astrocyte growth but not radiosensitivity.PMID 10537312Read ↗

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