Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Radiation resistance of normal human astrocytes: the role of non-homologous end joining DNA repair activity

11 Sept 2018

Abstract excerpt

Radiotherapy is a common modality for treatment of brain cancers, but it can induce long-term physiological and cognitive deficits. The responses of normal human brain cells to radiation is not well understood. Astrocytes have been shown to have a variety of protective mechanisms against oxidative stress and have been shown to protect neurons. We investigated the response of cultured normal human astrocytes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Repair Mechanisms
Share to Effects of Radiation Exposure
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30423138
DOI: 10.1093/jrr/rry084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Radiation resistance of normal human astrocytes: the role of non-homologous end joining DNA repair activityPMID 30423138Read ↗

DNA repair after irradiation in glioma cells and normal human astrocytesSemantic proximity Read ↗

DNA Damage in Mammalian Neural Stem Cells Leads to Astrocytic Differentiation Mediated by BMP2 Signaling through JAK-STATSemantic proximity Read ↗

A Role for Homologous Recombination and Abnormal Cell-Cycle Progression in Radioresistance of Glioma-Initiating CellsSemantic proximity Read ↗

P21 Overexpression Promotes Cell Death and Induces Senescence in Human GlioblastomaSemantic proximity Read ↗

Reparative properties of human glioblastoma cells after single exposure to a wide range of X-ray dosesSemantic proximity Read ↗

P21 Overexpression Promotes Cell Death and Induces Senescence in Human GlioblastomaSemantic proximity Read ↗

Irradiation induces glioblastoma cell senescence and senescence-associated secretory phenotype.Semantic proximity Read ↗

Cellular radiosensitivity: How much better do we understand it?Semantic proximity Read ↗

Cell transcriptional state alters genomic patterns of DNA double-strand break repair in human astrocytes.Semantic proximity Read ↗

Effects of acute low-moderate dose ionizing radiation to human brain organoidsSemantic proximity Read ↗

Mechanisms of Injury to Normal Tissue after RadiotherapySemantic proximity Read ↗

Ataxia telangiectasia mutated deficiency affects astrocyte growth but not radiosensitivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.