Article
Participation of the melanocortin-1 receptor in the UV control of pigmentation.
The journal of investigative dermatology. Symposium proceedings - 1 Sept 1999
Suzuki I, Im S, Tada A, Scott C, Akcali C, Davis M B, Barsh G, Hearing V, Abdel-Malek Z
Abstract excerpt
The cloning of the melanocortin-1 receptor (MC1R) gene from human melanocytes and the demonstration that these cells respond to the melanocortins alpha-melanocyte stimulating hormone (alpha-MSH) and adrenocorticotropic hormone (ACTH) with increased proliferation and melanogenesis have renewed the interest in investigation the physiological role of these hormones in regulating human pigmentation. Alpha-melanocyte...
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