Symmetric and asymmetric DNA N6-adenine methylation regulates different biological responses in Mucorales.

doi:10.1038/s41467-024-50365-2

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Article

Symmetric and asymmetric DNA N6-adenine methylation regulates different biological responses in Mucorales.

Nature communications - 18 Jul 2024

Lax Carlos, Mondo Stephen J, Osorio-Concepción Macario, Muszewska Anna, Corrochano-Luque María, Gutiérrez Gabriel, Riley Robert, Lipzen Anna, Guo Jie, Hundley Hope, Amirebrahimi Mojgan, Ng Vivian, Lorenzo-Gutiérrez Damaris, Binder Ulrike, Yang Junhuan, Song Yuanda, Cánovas David, Navarro Eusebio, Freitag Michael, Gabaldón Toni, Grigoriev Igor V, Corrochano Luis M, Nicolás Francisco E, Garre Victoriano

Abstract excerpt

DNA N6-adenine methylation (6mA) has recently gained importance as an epigenetic modification in eukaryotes. Its function in lineages with high levels, such as early-diverging fungi (EDF), is of particular interest. Here, we investigated the biological significance and evolutionary implications of 6mA in EDF, which exhibit divergent evolutionary patterns in 6mA usage. The analysis of two Mucorales species...

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PMID: 39025853
DOI: 10.1038/s41467-024-50365-2
PMCID: PMC11258239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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