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Article

Genomic analysis reveals variation between Mycobacterium tuberculosis H37Rv and the attenuated M. tuberculosis H37Ra strain.

Infection and immunity - 1 Nov 1999

Brosch R, Philipp W J, Stavropoulos E, Colston M J, Cole S T, Gordon S V

Abstract excerpt

Mycobacterium tuberculosis H37Ra is an attenuated tubercle bacillus closely related to the virulent type strain M. tuberculosis H37Rv. Despite extensive study, the reason for the decreased virulence of M. tuberculosis H37Ra has not been determined. A genomic approach was therefore initiated to identify genetic differences between M. tuberculosis H37Rv and M. tuberculosis H37Ra as a means of pinpointing the...

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Identifiers

PMID: 10531227
DOI: 10.1128/IAI.67.11.5768-5774.1999
PMCID: PMC96953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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