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Article

KIT protein expression and analysis of c-kit gene mutation in adenoid cystic carcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Oct 1999

Holst V A, Marshall C E, Moskaluk C A, Frierson H F

Abstract excerpt

The c-kit proto-oncogene encodes a transmembrane receptor tyrosine kinase (KIT), which is expressed in several normal human tissues, especially mast cells and interstitial cells of Cajal. Expression of KIT has been noted in several types of neoplasms and gene mutation has been shown as a mechanism of c-kit oncogene activation in some tumors. Recently, a single adnexal adenoid cystic carcinoma (ACC) was reported...

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Topics

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Share to Carcinoma, Adenoid Cystic
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Polymerase Chain Reaction

Share to Proto-Oncogene Mas

Share to Proto-Oncogene Proteins c-kit

Share to Salivary Gland Neoplasms

Share to Salivary Glands

Source

Identifiers

PMID: 10530560

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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