Article
KIT (CD117) Expression in Benign and Malignant Sweat Gland Tumors.
The American Journal of dermatopathology - 1 Dec 2015
Nishida Haruto, Daa Tsutomu, Kashima Kenji, Arakane Motoki, Urabe Shogo, Yoshikawa Yasuji, Gamachi Ayako, Yokoyama Shigeo
Abstract excerpt
KIT (CD117, c-kit) is a receptor tyrosine kinase involved in the tumorigenesis of several neoplasms. KIT is expressed by the secretory cells of normal sweat glands. We studied the KIT expression and KIT mutational status in various benign and malignant tumors of eccrine and apocrine glands. We included a total of 108 cases comprising 10 benign and 6 malignant sweat gland tumors, and KIT expression was...
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