Article
Methylation and gene mutation in eukaryotic DNA.
Acta biologica Hungarica - 1 Jan 1998
Liu C Q, Huang J F, Wang Y, Liu W B
Abstract excerpt
5-methylcytosine (m5C) as a rare base exists in eukaryotic genomes, which is a normal constitution in many eukaryotic DNA and the existence of m5C is a feature of eukaryotic DNA. Under regular physiological conditions, cytosine of eukaryotic DNA is usually methylated. Up to the present, many people consider that the m5C may be mutation hotspots by the deamination leading to gene mutation. Our study indicated that...
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