Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[The mechanism of replicative and post-replicative DNA methylation as a generator of mutations in a cell].

Molekuliarnaia biologiia - 1 Jan 2000

Mazin A L

Abstract excerpt

The functional role of enzymatic DNA methylation in eukaryotes is still obscure even 45 years after its discovery. In the present paper the analysis of various aspects of DNA methylation has been made from the point of view of a common functional model considering the system as a generator of 5mC-->T mutations in the cell. The mechanism and consequences of the reactions have been described in detail, from the 5mC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cellular Senescence
Share to Cytosine
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Replication

Share to Genome

Share to Methylation

Share to Mutation

Share to Thymine

Source

Identifiers

PMID: 8246940

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[The mechanism of replicative and post-replicative DNA methylation as a generator of mutations in a cell].PMID 8246940Read ↗

[Enzymatic DNA methylation as an aging mechanism].Semantic proximity Read ↗

Suicidal function of DNA methylation in age-related genome disintegration.Semantic proximity Read ↗

[Genome loses all 5-methylcytosine a life span. How is this connected with accumulation of mutations during aging?].Semantic proximity Read ↗

[Oxidation and deamination of nucleobases as an epigenetic tool].Semantic proximity Read ↗

[Loss of total 5-methylcytosine from the genome during cell culture aging coincides with the Hayflick limit].Semantic proximity Read ↗

[The influence of oxidized DNA on mammalian genome].Semantic proximity Read ↗

[Enzymatic repair of DNA and evolution of the genome].Semantic proximity Read ↗

Reasons of carcinogenesis indicate a big-bang inside: a hypothesis for the aberration of DNA methylation.Semantic proximity Read ↗

[Nuclear genetic material as an initial substrate for animal aging].Semantic proximity Read ↗

Replication and translation of epigenetic information.Semantic proximity Read ↗

How DNA lesions are turned into mutations within cells?Semantic proximity Read ↗

Methylation and gene mutation in eukaryotic DNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.