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[Oxidation and deamination of nucleobases as an epigenetic tool].

Postepy higieny i medycyny doswiadczalnej (Online) - 24 May 2012

Guz Jolanta, Jurgowiak Marek, Oliński Ryszard

Abstract excerpt

Recent discoveries have demonstrated that 5-methylcytosine (5mC) may be hydroxymethylated to 5-hydroxymethylcytosine (5hmC) in mammals and that genomic DNA may contain about 0.02-0.7% of 5hmC. The aforementioned modification is the key intermediate of active DNA demethylation and has been named "the sixth base in DNA". Although active DNA demethylation in mammals is still controversial, the most plausible...

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PMID: 22706113
DOI: 10.5604/17322693.997954

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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