Article
[Recent studies on mammalian DNA repair mechanisms].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jun 1995
Tsuzuki T, Tominaga Y
Abstract excerpt
Errors in the replication of DNA are a major source of spontaneous mutation and a number of cellular functions correct these errors to maintain a low frequency of spontaneous mutation. First, we focused on two enzymes, 8-oxo-dGTPase and O6-methylguanine-DNA methyltransferase, which may be involve...
Topics
- Animals
- DNA Repair
- DNA Replication
- Escherichia coli
- Humans
- Mutation
- Neoplasms
