Article
Linkage but lack of association for blood pressure and the alpha-adducin locus in normotensive twins.
Journal of hypertension - 1 Oct 1999
Busjahn A, Aydin A, von Treuenfels N, Faulhaber H D, Gohlke H R, Knoblauch H, Schuster H, Luft F C
Abstract excerpt
BACKGROUND: alpha-adducin is a cytoskeletal protein involved with sodium-pump activity in the renal tubule. The alpha-adducin gene locus has been linked to hypertension and a polymorphism identified which is associated with hypertension; however, the role of the alpha-adducin gene locus in normal blood pressure regulation is not defined. We performed a combined linkage and association study in normotensive...
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