Article
Lack of association between the alpha-adducin locus and essential hypertension in the Japanese population.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 1998
Kato N, Sugiyama T, Nabika T, Morita H, Kurihara H, Yazaki Y, Yamori Y
Abstract excerpt
Significant linkage and association of alpha-adducin, a cytoskeleton protein involved in transmembrane ion transport, with essential hypertension were recently shown in Caucasian populations, especially in relation to salt sensitivity. The present study investigated the relevance of this candidate gene to hypertension in a well-characterized Japanese population. A total number of 507 individuals were selected...
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