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Article

Postnatal development of the ob gene system: elevated leptin levels in suckling fa/fa rats.

The American journal of physiology - 1 Jul 1997

Rayner D V, Dalgliesh G D, Duncan J S, Hardie L J, Hoggard N, Trayhurn P

Abstract excerpt

The postnatal development of the ob gene system has been examined in Zucker fa/fa and +/fa plus +/+ (referred to as +/?) rats. White adipose tissue was taken from animals aged 1 to 28 days. Before weaning, white fat was predominantly subcutaneous, the amount increasing rapidly after birth. ob mRNA was detected by Northern blotting in samples of inguinal fat at 1 day of age and thereafter. Circulating leptin,...

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Identifiers

PMID: 9249584
DOI: 10.1152/ajpregu.1997.273.1.R446

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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