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Article

Cytoskeletal reorganization induced by engagement of the NG2 proteoglycan leads to cell spreading and migration.

Molecular biology of the cell - 1 Oct 1999

Fang X, Burg M A, Barritt D, Dahlin-Huppe K, Nishiyama A, Stallcup W B

Abstract excerpt

Cells expressing the NG2 proteoglycan can attach, spread, and migrate on surfaces coated with NG2 mAbs, demonstrating that engagement of NG2 can trigger the cytoskeletal rearrangements necessary for changes in cell morphology and motility. Engagement of different epitopes of the proteoglycan results in distinct forms of actin reorganization. On mAb D120, the cells contain radial actin spikes characteristic of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10512873
DOI: 10.1091/mbc.10.10.3373
PMCID: PMC25605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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