Article
The use of differential scanning calorimetry (DSC) to determine the correctness of folding of cloned proteins.
Biotechnology and applied biochemistry - 1 Oct 1999
Brewer J M
Abstract excerpt
The advantages and limitations of use of the differential scanning calorimetry technique to determine whether cloned and expressed mutant proteins are folded correctly are explained and discussed. Examination of stabilization of these proteins to thermal denaturation by specific ligand binding can provide the required information.
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